pentobarbital will lower the extent or effect of estradiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.pentobarbital will decrease the extent or influence of cinacalcet by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.Barbiturates are metabolized largely from the hepatic mic… Read More